NEW DELHI, May 29: A Paris-based institute is claimed to have found that the Pfizer vaccine is slightly less effective but appears to still protect against the more transmissible Covid variant found in India.
According to a study by France’s Pasteur Institute, “Despite slightly diminished efficacy, the Pfizer vaccine probably protects” against the variant found in India the laboratory test results showed,” Olivier Schwartz, the institute’s director and co-author of the study that was published on the BioRxiv website ahead of peer review, said.
The study sampled 28 healthcare workers in the city of Orleans. Sixteen of them had received two doses of the Pfizer vaccine, while 12 had received one dose of the AstraZeneca vaccine.
People who had received two doses of Pfizer saw a three-fold reduction in their antibodies against B.1.617 variant, according to the study, but were still protected.
“The situation was different with the AstraZeneca vaccine, which induced particularly low levels of antibodies neutralising” the variant, the study said.
Patients who had had Covid-19 within the past year and people vaccinated with two doses of Pfizer retained enough antibodies to be protected against the variant found in India, but three to six times less antibodies than against the UK variant, Schwartz said.
The study shows that “this variant.. has acquired partial resistance to antibodies,” Schwartz said.
Since first emerging in late 2019 in China, the SARS-CoV-2 virus that causes Covid-19 has developed several variants, usually named for the places where it first appeared including the so-called South Africa and UK strains. The variant first detected in India appears to be much more transmissible than earlier variations.
The government of India, however, has taken strong objections for the strain to be called the “Indian variant” and insist that it must be identified only as “B.1.617 variant” as the number given by the World Health Organisation. This variant has now been officially recorded in 53 territories, according to a WHO report.
(Manas Dasgupta)